Tick-borne encephalitis

Tick-borne encephalitis (TBE) is a viral infection usually transmitted through the bite of an infected tick. The disease occurs in parts of central, northern and Eastern Europe, Siberia and parts of Asia. Ticks are found on forest fringes within adjacent grassland, forest glades, riverside meadows and marshland, forest plantations with brushwood and shrubbery. Ticks can also be found in parks and gardens.

Travellers to areas where TBE occurs may be at risk when walking, camping or working in woodland. In Europe, early spring through to late autumn are generally higher risk, but seasons vary according to location. Since 2011, six confirmed cases of TBE have been reported in the UK. All had history of travel to the TBE endemic areas of Europe.

Typically, the disease occurs in two stages: a mild flu-like illness and a potentially serious infection of the central nervous system (brain and spinal cord). TBE is rarely fatal in Europe: however in Asia it can be fatal in up to 20 percent of cases. Long-term neurological complications are common.


Travellers should:

TBE vaccination is available for those travellers intending to visit rural risk areas, or whose occupation may put them at higher risk (see below).

Tick-borne encephalitis vaccine

TBE vaccine should be considered for:

  • All persons living in TBE risk areas
  • Those at occupational risk in risk areas: farmers, forestry workers, soldiers
  • Travellers at risk of disease
  • Laboratory workers who may be exposed to TBE

Vaccination schedule

Vaccine Schedule Accelerated schedule Length of protection
(16 years and older)


TicoVac Junior®
(above 1 year and below 16 years)
3 doses on days 0, between 1 and 3 months, and 5 to 12 months after the second dose* 2nd dose can be given 2 weeks after the 1st dose **First booster no more than 3 years after 3rd dose. After this, boosters may be given at 5 year intervals if at risk
*After the first two doses, sufficient protection can be expected for the on-going tick season (protection rate over 90 percent after the second dose)
**In those aged > 60 years, booster intervals should not exceed three years (see below)


First published : 22 November 2018 Last updated : 06 July 2023

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Recent News on Tick-borne encephalitis

Tick-borne encephalitis risk: practical advice during vaccine shortage

An important reminder of practical aspects of tick-borne encephalitis prevention for health professionals and travellers

Updated: 05 February 2024

Changes to the Country Information pages: Tick-borne encephalitis

NaTHNaC has reviewed and updated country-specific tick-borne encephalitis information and vaccine recommendations

Updated: 27 October 2023

Recent Tick-borne encephalitis Outbreaks

12 July 2023

Tick-borne encephalitis in France

As of 7 July 2023, the French authorities confirmed that a total of 61 locally acquired tick-borne encephalitis (TBE) cases were reported from May 2021 to May 2023. The Auvergne-Rhône Alpes region is now an important area of TBE circulation; with Haute-Savoie department reporting the highest number of cases in this two year period, and cases now reported in Ardèche department.

Take usual precautions

15 March 2023

Tick-borne encephalitis in Germany

As of 2 March 2023, new tick-borne encephalitis risk areas have been confirmed; Anhalt-Bitterfeld district in Saxony-Anhalt; Furstenfeldbruck and Munich districts in Bavaria.

Take extra precautions