Travel and mental health

Travel health advice for travellers and health professionals

Key messages

  • Travel-related stress has the potential to exacerbate a pre-existing mental health condition, so effective preparation is key.
  • As with any underlying illness, travelling with an unstable or newly diagnosed condition is not recommended.
  • All travellers should ensure they have comprehensive travel health insurance and declare all pre-existing health conditions.
  • Careful consideration should be given to the availability of replacement medication and emergency mental health services at the traveller’s chosen destination/s.


Mental health conditions incorporate a broad range of illness with different symptoms. However, they are generally characterised by a combination of abnormal thoughts, behaviours, emotions and relationship difficulties [1]. They include addictions such as alcohol or drug misuse, anxiety, bipolar conditions, depression, eating disorders like anorexia nervosa and bulimia, obsessive compulsive disorders, paranoia, personality disorders, phobias, post-traumatic stress disorder, psychosis and schizophrenia [2].

Although often hidden, mental health conditions are common, representing the largest single cause of disability in the United Kingdom (UK). Anyone can be affected: adults (including new parents), children, older people and teenagers [3]. Approximately one in four people in the UK are diagnosed with at least one mental health problem every year [3, 4].

Most mental health conditions can be successfully treated [1]. Common UK treatments include talking therapies such as cognitive behavioural therapy, and if appropriate, prescription drugs relevant to the underlying diagnosis [5, 6]. Daily self-management routines incorporating regular exercise, eating well and getting plenty of sleep can also be effective in helping people cope with mental health conditions [7].

The World Health Organization (WHO) states that mental health issues are one of the leading causes of ill health among travellers, with psychiatric emergency being one of the most common reasons for medical air evacuation. Various factors, including traveller isolation caused by geographical distance from family, friends and familiar social support systems, freedom from behavioural norms and the impact of different cultures can contribute to this [8].

Facilities and resources available to those experiencing mental health issues, as well as the understanding of these conditions, vary greatly in different countries [9].

Before travel

Travel can be an enhancing life experience, but may also be a destabilising life event, particularly for those with mental health conditions. Pre-travel advice is crucial to decrease risk of an exacerbation of their condition in these higher-risk individuals [10]. If potential hazards are recognised and anticipated, with appropriate preparation and plans in place, individuals with mental health conditions, can remain safe and well when they travel [8].

As with any underlying medical issue, coping with travel-related stress can potentially exacerbate any pre-existing mental health conditions [8, 10]. Any individual with a poorly controlled or newly diagnosed condition, whether physical or psychological, is advised to delay travel until their condition is stable.

An individual with a well-controlled mental health condition planning a trip abroad should be encouraged to research their destination carefully [9]. They should discuss their travel plans with friends, family, and a health professional, including their mental health professional, psychiatrist and/or community psychiatric nurse, if applicable, before booking. Given the natural stress of travel, inactive conditions can remerge, undiagnosed problems may become apparent and new problems arise. In addition, travellers may suffer from anxiety and aggravated symptoms triggered by jet lag, fatigue, work or family pressures [11].

Travellers with a fear of flying can be referred to specialised courses run by airlines, when available.

Individuals with newly diagnosed and/or unstable mental health conditions, who feel that travel is essential, should be encouraged to consider the impact of an exacerbation of their condition overseas, both on themselves, and their friends and family. A mental health crisis while travelling can be a frightening experience for the individual, may result in long-term consequences such as arrest or detention, and can be difficult for local medical facilities to manage. Medical repatriation for an episode of mental illness is expensive and logistically challenging [12]. The effect on friends or family accompanying the traveller and/or those at home trying to help from a distance, should not be underestimated. If a traveller is unwilling to reconsider their travel plans, they should discuss their trip with a health professional, including how they can access emergency care if their mental health deteriorates abroad. This can be included in an existing care plan, if the traveller already has one [9].

Travellers with a history of substance dependency should be aware that unfamiliar environments, language barriers and cultural difficulties can increase stress levels and trigger the need to use substances. Seeking prohibited substances abroad (which in some countries includes alcohol) can lead to criminal charges, fines and imprisonment [13].

Adjustment difficulties can be more acute for individuals with underlying mental health conditions who travel or live abroad for work. Understanding stress factors, identifying early symptoms and signs of mental health issues, and implementing strong procedures to mitigate mental health risks, can help organisations protect their employees abroad [14]. Travellers based abroad for long periods, can learn self-monitoring techniques and stress-reduction strategies before departure or during their stay [8].


All travellers with underlying health issues should carry a letter from their doctor providing clinical details of their condition, treatment and certifying the need for drugs and/or other medical items. Ideally, this should be documented in a language understood at the traveller's chosen destination [8]. Extra medication supplies, including if appropriate emergency medication, should be carried. Travellers should consider any restrictions on the type and amount of medicines they carry and ensure that they have appropriate documentation when crossing borders [11]. See Medicines and travel factsheet. On flights, medication should be carried in hand luggage, with an extra supply in the hold luggage. Medication stored in hold luggage is at risk of extremes of temperature and is more likely to be lost or stolen.

During travel, difficulties in following usual drug regimes and/or replacing lost or stolen medication can exacerbate an underlying condition [9, 10]. For example, a traveller without access to their usual mood-stabilising medication could experience a manic episode, resulting in risk-taking behaviour or attempts to self-medicate with alcohol or illegal drugs. Unfortunately, a traveller in a foreign country exhibiting aggressive, strange or psychotic behaviour is often arrested by police or security forces, which can lead to a rapid deterioration in their mental status [12].

Travellers who need to arrange blood tests to check medication levels while travelling, should investigate laboratory facilities at their destination/s before they depart. For example, individuals taking a mood-stabilising drug such as lithium need regular blood tests to check for drug toxicity [15]. This may be challenging to arrange in some locations [11]. Environmental factors, such as heat and humidity, can lead to increased sweating, which in turn can elevate blood lithium levels [11].


If visiting European Union (EU) countries travellers should carry a Global Health Insurance Card (GHIC) (previously a European Health Insurance Card) as this will allow access to state-provided healthcare in some countries, at a reduced cost, or sometimes for free. A GHIC, however, is not an alternative to travel insurance. Check the GOV.UK website for guidance. Unlike the UK, most countries do not provide free healthcare and access to appropriate emergency mental health services may be limited or non-existent. In some countries, mental health conditions are stigmatised, with little or no medical care available in the mainstream medical system [8, 12].

Comprehensive travel insurance covering all activities and destinations is essential for all travellers. A full declaration of past and current medical conditions and their treatment should be made. Some insurance companies exclude cover for mental health conditions; others will require the traveller to undergo a medical screening procedure. Travellers should read the full details of any policy, including the exemptions, and ensure costs of treatment abroad and medical evacuation for mental health conditions are covered [9].

Malaria prevention

Malaria advice and antimalarial recommendations for individual countries can be found on our Country Information pages.

Antimalarial recommendations should be tailored to individual needs, taking into account possible risks and benefits. As part of a stringent risk assessment, it is essential that a full clinical history is obtained, detailing current medication, significant health problems and any known drug allergies [16]. Travellers should be encouraged to provide a comprehensive medical and drug history. If possible, choice of chemoprophylaxis should be made in consultation with a traveller's mental health specialist or psychiatrist (when applicable).

The antimalarial drug mefloquine (trade name Lariam®) is contraindicated in all travellers with a current or previous history of depression (even mild depression), generalised anxiety disorder, psychosis, schizophrenia, self-endangering behaviour, suicide attempts, suicidal thoughts or any other psychiatric disorder [17, 18]. This includes eating disorders. Risk of serious mental health disorders is also higher in first degree relatives of individuals diagnosed with these conditions [17].

Increased psychiatric adverse events have been reported with mefloquine use, especially in women, as compared atovaquone plus proguanil (trade names: Malarone® and Maloff Protect®) and doxycycline [17].

Mefloquine may induce psychiatric symptoms such as anxiety disorders, paranoia, depression, hallucinations and psychosis. Psychiatric symptoms such as insomnia, abnormal dreams/nightmares, acute anxiety, depression, restlessness or confusion have to be regarded as prodromal for a more serious event. Cases of suicide, suicidal thoughts and self-endangering behaviour, such as attempted suicide have been reported [18].

Potential drug interactions with any current medication should be carefully considered. Use of drug interaction checker tools such as the British National Formulary/National Institute for Health and Clinical Excellence List of Drug Interactions is recommended.

All travellers visiting malaria risk regions should be advised of the ABC and D of malaria prevention.


All individuals should follow current UK recommendations to reduce their risk of catching COVID-19 and passing it on to others.

General guidance regarding risk assessment for travel during the COVID-19 pandemic and information about the COVID-19 vaccination programme is available.


Vaccine recommendations for individual countries can be found on our Country Information pages and tailored to an individual traveller's requirements and medical history. Mental health conditions themselves are not contraindications to vaccines.

During travel

Crowds, noise and the general stimulation of transport hubs like airports and stations can be psychologically challenging. Extended journeys, with long periods of sitting, relative confinement, alcohol intake, dehydration, altered food intake, tiredness, disruption of circadian rhythms and jetlag can contribute to anxiety and agitation [10, 19].

Long distance travel is known to aggravate pre-existing psychosis [10, 20]. Unfamiliar environments, disrupted daily routines, language barriers, difficulty understanding social mores and use of psychoactive substances can threaten mental well-being and trigger a psychotic episode in any traveller. Individuals with underlying conditions, such as schizophrenia, are more susceptible and should familiarise themselves with their stress factors and the warning signs that could lead to a psychotic episode [19].

Maintaining a routine and making time for activities that protect their mental health benefits all travellers [7], but is especially important for individuals with pre-existing conditions. Such travellers should ensure they are aware of their physical and mental limits, get plenty of sleep, eat well and avoid psychoactive substances like alcohol or cannabis. Ideally, whenever possible they should avoid travelling alone [19].

Alcohol is often used to ease fears associated with travel, but constitutes an important travel-associated mental health risk. Excessive alcohol consumption on flights can result in a loss of inhibition and explosive anger commonly known as air rage [10].

WHO advise travellers to discuss and develop coping strategies before they depart [8].

Potential coping mechanisms include:

  • Booking the most direct route possible.
  • Ideally travelling with a friend or family member.
  • Identifying a reputable mental health professional at the destination who speaks the same language.
  • Allowing plenty of time to arrive and go through security checks.
  • Bringing a calming item: book, journal or mobile device.
  • Learning relaxing/breathing exercises, meditation/mindfulness techniques and stretching exercises.
  • Getting enough sleep, eating properly and drinking plenty of non-alcoholic fluids.
  • Taking medication routinely and consistently.
  • Avoiding alcohol.
  • Maintaining a positive attitude, being flexible and trying to adapt circumstances while abroad.
  • Keeping in touch with family, friends and (if applicable) health professionals at home [19, 21].

Checking information before travel, such as type of transport, timing/length of journeys, destination details and easy to predict difficulties like delays, can help travellers develop coping strategies. This allows them to stay independent and may help avoid exacerbating pre-existing disorders [8].

Staying in touch with family, friends and/or carers is important. Simple strategies like arranging international roaming for mobile phones and buying the correct adaptor for battery recharging helps avoid becoming isolated [9].

A mental health condition does not in itself increase the likelihood of acquiring a food and water-borne illness, but behavioural factors may increase risk of exposure. For example, a traveller experiencing a depressive episode may find it hard to follow safe food and water advice or ensure effective personal hygiene.

All travellers should follow good food and water hygiene advice and be aware of how to treat travellers' diarrhoea.

After travel

Travellers who experience an exacerbation or re-emergence of a pre-existing condition should get medical help immediately on their return to the UK, ideally with their usual care providers. If available, details of any treatment and medication given abroad are helpful for health professional supporting returning travellers.


  1. World Health Organization. Mental disorders. 8 June 2022. [Accessed 2 November 2023]
  2. World Health Organization. International Classification of Disease, Eleventh Revision (ICD-11). [Accessed 2 November 2023]
  3. Independent Mental Health Taskforce to the NHS in England. The Five Year Forward View for Mental Health. February 2016. [Accessed 2 November 2023]
  4. House of Commons Library. Mental health services in England. 9 October 2023. [Accessed 2 November 2023]
  5. National Collaborating Centre for Mental Health commissioned by National Institute for Health & Clinical Excellence. Common Mental Health Disorders Identification and Pathways to Care. 2011. British Psychological Society/Royal College of Psychiatrists. [Accessed 2 November 2023]
  6. Mind. Mental health problems - an introduction. What treatments are available? 2023 © Mind. This information is published in full at [Accessed 2 November 2023]
  7. Mental Health Foundation. Be travel aware. 2018.
  8. World Health Organization. Health risks when travelling. Is risk to mental health increased when travelling? How can I reduce risks to mental health when travelling? 28 April 2020.[Accessed 2 November 2023]
  9. Foreign, Commonwealth and Development Office. Mental health and wellbeing abroad. Last updated 11 July 2023. [Accessed 2 November 2023]
  10. Seeman M. Travel Risks for Those With Serious Mental Illness. Int J Travel Med Glob Health. 25 September 2016;4(3):76-8. [Accessed 2 November 2023]
  11. US Centers for Disease Control and Prevention. Mental Health.. In: Health Information for International Travel. Last reviewed 1 May 2023. [Accessed 2 November 2023]
  12. Felkai P, Kurimay T. Patients with mental problems - the most defenceless travellers. J. Trav Med. 1 September 2017;24 (5). [Accessed 2 November 2023]
  13. International Association for Medical Assistance to Travelers. Travel and Substance Use. Last updated 11 December 2020. [Accessed 2 November 2023]
  14. Eyears J. Business travel, working abroad and mental health: a wake-up call. Occupational; health and wellbeing. Personnel Today. Published online 31 March 2018. [Accessed 2 November 2023]
  15. Sanofi. Summary of Product Characteristics. Priadel (Lithium carbonate 400mg). Last updated 3 October 2023. [Accessed 2 November 2023]
  16. UK Health Security Agency. Chemoprophylaxis. Guidelines for malaria prevention in travellers from the UK. Last updated 19 September 2023. [Accessed 2 November 2023]
  17. UK Health Security Agency . Mefloquine. Guidelines for malaria prevention in travellers from the UK. Last updated 19 September 2023. [Accessed 2 November 2023]
  18. Roche Products Limited. Lariam 250mg Tablets (mefloquine hydrochloride). Last updated 8 July 2022. [Accessed 2 November 2023]
  19. International Association for Medical Assistance to Travelers: Travel and Psychosis. Last reviewed 11 December2020. [Accessed 2 November 2023]
  20. Airault R, Valk T. Travel-related psychosis (TrP): a landscape analysis. Journal of Travel Medicine.1 January 2018; 25 (1). [Accessed 2 November 2023]
  21. International Association for Medical Assistance to Travelers. Travelling with anxiety: Coping on-the-go. 16 May 2017. [Accessed 2 November 2023]

First published : 22 November 2018 Last updated : 02 November 2023
  1. COVID-19 advice updated and content re-ordered.

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